Title

Predictive Recognition of Native Proteins by Cucurbit[7]uril in a Complex Mixture

Document Type

Article

Publication Date

7-14-2016

Abstract

The recognition of human growth hormone (hGH) by the synthetic host molecule cucurbit[7]uril (Q7) was predicted on the basis of its N-terminal phenylalanine. An aqueous-compatible resin with covalently immobilized Q7 groups was prepared and shown to recognize native insulin and hGH in simple and complex mixtures.

Document Object Identifier (DOI)

10.1039/c6cc03193e

Publication Information

Chemical Communications

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