Inspired originally by peptides that traverse biological barriers, research on molecular transporters has since identified the key structural requirements that govern cellular entry, leading to new, significantly more effective and more readily available agents. These new drug delivery systems enable or enhance cellular and tissue uptake, can be targeted and provide numerous additional advantages of significance in imaging, diagnostics and therapy.
Document Object Identifier (DOI)
Wender, P.A., Cooley, C.B., & Geihe, E.I. (2012). Beyond cell penetrating peptides: Designed molecular transporters. Drug Discovery Today: Technologies, 9(1), e49-e55. doi:10.1016/j.ddtec.2011.07.004
Drug Discovery Today: Technologies