A general branching process model is suggested to describe cell cycle desynchronization. Cell cycle phase times are modeled as random variables and a formula for the expected fraction of cells in S phase as a function of time is established. The model is compared to data from the literature and is also compared to previously suggested deterministic and stochastic models.
Olofsson, P., & McDonald, T.O. (2010). A stochastic model of cell cycle desynchronization. Mathematical Biosciences, 223(2), 97-104. doi: 10.1016/j.mbs.2009.11.003